THE ULTIMATE GUIDE TO GR

The BclI GR polymorphism comprises a C to G nucleotide substitution at 646 bp downstream of exon 2 in intron B in the human GR gene that produces a slicing web-site to the BclI restriction enzyme. G-allele of the polymorphism boosts tissue sensitivity to glucocorticoids as demonstrated by greater suppression of serum cortisol stages just after